Molecular characteristics of serrated adenomas of the colorectum
نویسندگان
چکیده
منابع مشابه
Synchronous and subsequent lesions of serrated adenomas and tubular adenomas of the colorectum.
The characteristics of synchronous and subsequent lesions of serrated adenomas (SAs) of the colorectum are still unclear. This study aimed to clarify the characteristics of synchronous and subsequent lesions of SAs compared with tubular adenomas (TAs) of the colorectum. Patients were divided into 2 groups: SA (127 patients) and TA (158 patients). The mean follow-up durations in the SA and TA gr...
متن کاملInfrequent K-ras codon 12 mutation in serrated adenomas of human colorectum.
BACKGROUND Serrated adenoma is a new morphological subtype of colorectal adenoma. The lesion provides a distinct morphological route to carcinoma, but the underlying genetic changes have not yet been investigated. AIMS To determine the frequency of K-ras mutation in serrated adenoma. METHODS The frequency of K-ras codon 12 point mutation in 20 serrated adenomas, five atypical hyperplastic p...
متن کاملSerrated adenomas of the cardia.
Adenomas of the stomach are histologically classified into tubular and villous adenomas, mixed (tubulovillous) and papillary phenotypes being also recognized. They are localized in the antrum and the body. In a previous work we reported a case of serrated adenoma of the cardia having, at the time of diagnosis, an invasive growth. In this communication we report five newly identified cases of se...
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AIMS A review of the literature indicated that only one case of serrated adenoma of the appendix has been recorded. The aim was to explore the possible occurrence of serrated adenomas of the appendix at the department of pathology, Karolinska Institute and University Hospital, Stockholm, Sweden. METHODS Between January 1993 and December 2003, 38 non-carcinoid, non-neoplastic, or neoplastic po...
متن کاملThe clinical importance of serrated lesions of the colorectum.
Colorectal cancer (CRC) is the third most common cancer in the world. Fortunately, it is also proven to be one of the most preventable cancers, in large part due to the utilization of CRC screening. Historically, it was believed that the adenomatous polyp was the only precursor to carcinoma of the colorectum. Within the last decade, it has been shown that approximately 20-30% of sporadic colon ...
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ژورنال
عنوان ژورنال: Gut
سال: 2002
ISSN: 0017-5749
DOI: 10.1136/gut.51.2.200